Treponema pallidum is a motile spirochaete that is generally acquired by close sexual contact, entering the host via breaches in squamous or columnar epithelium. T. pallidum is causing Syphilis – a sexually transmitted infection. The primary route of transmission is through sexual contact; it may also be transmitted from mother to fetus during pregnancy or at birth, resulting in congenital syphilis.
- Scrapings of epithelial cells (urethral, cervical, vaginal)
- Tissue fluid from erosive and ulcerative lesions of the skin and mucous membranes.
- FAM (495 – 520 nm) for Internal Control (IC)
- ROX (575 – 602 nm) for Treponema pallidum DNA