HSV-1 is an oral form of herpes, which typically affects the mouth and surrounding areas on the face. In addition HSV-1 can cause encephalitis, keratoconjunctivitis, stomatitis and skin infections. Transmission generally occurs through saliva and rarely through sex contact.
HSV-2 causes most cases of genital herpes as well as the neurological manifestations such as meningitis and radiculitis. Pregnant women and infants are risk groups for HSV infections, since when infants do contract neonatal herpes, they may suffer serious neurological damage, mental retardation or death. In addition HSV-2 is known to increase a person’s risk of contracting HIV.
- Blood serum, plasma
- Swabs of epithelial cells
- Tissue fluid
- Erosive-ulcerative skin lesions
- Cerebrospinal fluid
- Prostatic fluid
- Bronchoalveolar lavage
- Whole blood
- FAM (495 – 520 nm) for Internal Control (IC)
- HEX (535 – 554 nm) for HSV-1 DNA
- ROX (575 – 602 nm) for HSV-2 DNA