RealLine EGFR Detect 7R

RealLine EGFR Detect-7R Kit for the detection of mutations in EGF-Receptor Genes.

RUO – Research Use Only

 

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Description

Description

The RealLine EGFR 7R Kit is detecting  and differentiating following mutations:

  • Deletions and complex mutations in exon 19
  • L858R
  • L861Q
  • G719X – detected but not genotyped G719S, G719A, G719C
  • S768I
  • T790M

Non-small cell lung cancer (NSCLC) is the most common type of the lung cancer. Activating somatic mutations within the tyrosin kinase (TK) domain in the epidermal growth factor receptor (EGFR) protein are associated with sensitivity of tumors to EGFR-TK inhibitors. So patients with tumors harboring either of these mutant forms of EGFR are extremely sensitive to the selective EGFR-tyrosine kinase (TK) inhibitors like Gefitinib, Erlotinib or other anti-EGFR-therapy.

RealLine Cycler 48 or RealLine Cycler 96 (BIORON Diagnostics GmbH)

CFX96, iQ5 iCycler (Bio-Rad, USA)

DT96, DTLite (DNA-Technology, Russia)

Our kits can be used with other Real-Time cyclers from ABI, Roche, Agilent etc.
Please read the IFU properly and ask us for recommendations of device settings!

IFU -MED21811_21812

pdf
Additional information

Additional information

RealLine EGFR Detect 7R RUO

12 Tests, 36 Tests

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