In vitro diagnosticum


Product name Cat.No. Format Packsize
RealLine TBEV (Str-format), CE - IVD
VBD1198 Str 48 Tests
RealLine TBEV (Fla-format), CE - IVD
VBD1199 Fla 50 Tests

TBEV is endemic in an area ranging from northern China and Japan, through far-eastern Russia to Europe. TBEV is transmitted by the bite of infected ticks (Ixodes scapularis, Ixodes ricinus and Ixodes persulcatus), or (rarely) through the non-pasteurized milk of infected cows, sheeps and goats. TBE is a viral infectious disease involving the central nervous system (CNS). The disease is incurable once manifested, so there is no specific drug therapy for TBE.


The RealLine TBEV kits are designed for sensitive direct detection of TBEV RNA in clinical samples by one-step real-time RT-PCR. The kits are designed for in vitro diagnostics and provides qualitative detection.

Sample Material

  • Blood serum, plasma
  • Cerebrospinal fluid
  • Tick suspension samples

Real-Time PCR Detection Channels

  • FAM (495-520 nm)
  • Internal Control IC
  • ROX (575-602 nm)
  • TBEV RNA and Positive Control

Validated Cyclers

  • RealLine Cycler 96 and RealLine Cycler 48 (BIORON Diagnostics GmbH)
  • Str, Fla, Uni
  • iQ™ iCycler, iQ5™ iCycler, CFX96™ (Bio-Rad, USA)
  • Str, Fla, Uni
  • DT96, DTLite (DNA-Technology, Russia)
  • Str, Fla, Uni
  • Rotor-Gene® 3000, Rotor-Gene® 6000 and Rotor-Gene® Q (Qiagen, Germany)
  • Uni, Fla
  • Eco48, (PCRMax, GB)
  • Fla

Our kits can be used with other real-time cyclers from companies ABI, ROCHE, Agilent etc. Please read the IFU properly, and ask us for recommendations for the settings.